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Spectinomycin (As Dihydrochloride Pentahydrate)
Lincomycin ( As Hydrochloride)
LINOVAC is a broad spectrum antibacterial and antimycoplasma, it is indicated for the treatment and prevention of chronic respiratory diseases ( CRD) associated with mycoplasma and coliform infections in growing poultry.
GENERAL PHARMACOLOGICAL DOSE:
Poultry: 150 mg antibiotic activity /kg body weight / day
DOSAGE :
Each pack gives 100 gm combined antibiotic activity :
Poultry: 150gm LINOVAC / 200 Liters of drinking water.
Treatment of CRD:
Administer 75 mg LINOVAC / kg body weight / day at the first signs of disease and continue for three to seven days.
LINOVAC is a combination of Lincomycin and Spectinomycin . Lincomycin a bacteriostatic antibiotic derived from Streptomyces lincolnensis, active against gram-positive bacteria, obligate anaerobes and mycoplasma but has little activity against gramnegative organisms. Lincomycin exerts its antibacterial action by inhibiting RNA-dependent protein synthesis by acting on the 50S subunit ribosome.
Spectinomycin is an aminocyclitol antibiotic produced by Streptomyces spectabilis. It is active against some gram positive and gram-negative bacteria. It exerts its bacterostatic effect by binding to the 30S subunit of bacterial ribosomes and inhibiting the translation of protein synthesis. It is not well absorbed after oral administration.